United Pet Club

Pituitary pars intermedia dysfunction

Also known as: Equine Cushing's disease

Pituitary pars intermedia dysfunction (PPID), historically called equine Cushing's disease, is a progressive degenerative disorder of the pituitary gland in older horses and donkeys. Loss of dopamine control leads to overproduction of pituitary hormones. The classic sign is a long, curly coat that fails to shed.

Quick facts

Type:
Disease
Typical onset:
Insidious
Body systems:
Endocrine, Metabolic
Affected species:
DONKEY, HORSE

Sources & references

  • Merck Veterinary Manual — Covers the pathogenesis, signs, and pergolide treatment of equine PPID.
  • Wikipedia — General reference on equine Cushing's disease and its clinical features.

This content is for educational purposes and is not a substitute for professional veterinary advice. If you are worried about your pet, contact your veterinarian.