Genetic diversity for breeders: why it matters and how to protect it
Why a shrinking gene pool causes more inherited disease, not less, and the concrete steps, outcrossing, genetic testing, and sire limits, that keep a breeding program healthy.
针对已知的遗传病给一对配种对象做检测,可以排除那些已经研究得比较清楚的风险。但它没办法排除所有问题,因为不是每种病都已经找到相应的基因标记,尽管如此,在定下配对之前,这还是目前最实用的方法。
起源族群比较小的品种,整体的遗传多样性会比较低,不管某一项检测结果怎样,这都会拉高好几种疾病的基本风险。这也是为什么有些品种俱乐部会积极鼓励外系繁殖(outcrossing)。
不能。它只涵盖那些已经找到基因标记的疾病。新的标记还在不断被发现,所以检测结果干净并不代表绝对没事。
说的是一个品种族群里头,不同基因变异的范围。多样性越低,遗传病一代代传下去扩散开来的风险就越高。
Why a shrinking gene pool causes more inherited disease, not less, and the concrete steps, outcrossing, genetic testing, and sire limits, that keep a breeding program healthy.
A practical guide to genetic screening for dog and cat breeders: what the tests detect, how to read the results, and how to pair animals responsibly.