Histiocytic sarcoma
Histiocytic sarcoma is an aggressive cancer of histiocytes, immune cells related to macrophages and dendritic cells, with a strong breed predisposition in Bernese Mountain Dogs, Flat-Coated Retrievers, and Rottweilers. It can be localized, often around a joint or in an organ, or disseminated through multiple organs. The disease tends to progress rapidly and spread widely, making it one of the more difficult canine cancers to treat.
Quick facts
- Type:
- Neoplasia
- Typical onset:
- Subacute
- Body systems:
- Hemolymphatic, Immune, Multisystemic
- Affected species:
- DOG
- Reference codes:
- ICD11 2B31.1
Sources & references
- Merck Veterinary Manual — Describes localized and disseminated histiocytic sarcoma and its marked predisposition in Bernese Mountain Dogs.
- OMIA — Records histiocytic sarcoma susceptibility in the dog, notably in predisposed breeds.
- ICD-11
This content is for educational purposes and is not a substitute for professional veterinary advice. If you are worried about your pet, contact your veterinarian.