L-2-hydroxyglutarsyreuri

Also known as: L2HGA

Hereditary

En arvelig neurometabolisk sygdom forårsaget af mutationer i L2HGDH-genet, som fører til ophobning af L-2-hydroxyglutarsyre og fremadskridende hjernedysfunktion. Den er bedst kendt hos Staffordshire bullterrier og beslægtede racer. Ramte hunde viser episodiske rystelser, ataksi, demens og kramper, som ofte forværres af ophidselse eller motion.

Quick facts

Type:: Genetic
Typical onset:: Insidious
Body systems:: Nervous, Metabolic
Affected species:: DOG
Reference codes:: ICD11 5C50.E1

Sources & references

OMIA — OMIA phene entry for L-2-hydroxyglutaric aciduria associated with L2HGDH in the dog.
Wikipedia — General overview of L-2-hydroxyglutaric aciduria including the canine form.
ICD-11

This content is for educational purposes and is not a substitute for professional veterinary advice. If you are worried about your pet, contact your veterinarian.